BonniDune Kennel is located in
Southern Indiana, USA. Although I started
with German Shepherd Dogs, today BonniDune is
dedicated to showing, trialing and producing
sound, versatile Border Collies.
BonniDune is proud to be recognized as an AKC Breeder of Merit.

Puppies Born December 25, 2013

Is Trifexis Safe For Border Collies


Trifexis is a popular monthly oral medication used for the prevention and treatment of fleas, heartworms, hookworms, roundworms, and whipworms in dogs. However, as with any medication, pet owners should consider the safety and potential side effects, especially when it comes to specific breeds such as Border Collies. This article aims to explore whether Trifexis is safe for Border Collies.

Understanding Border Collies

Border Collies are highly intelligent and energetic dogs known for their herding abilities. They are generally healthy and have a life expectancy of around 12-15 years. However, this breed may have certain sensitivities and genetic predispositions that should be taken into account when choosing a medication.

The Safety of Trifexis

Trifexis is generally regarded as safe for most dogs, including Border Collies. It has been extensively tested and approved by the U.S. Food and Drug Administration (FDA) for use in dogs. However, it is always recommended to consult with your veterinarian before starting any new medication, as they can provide personalized advice based on your dog’s specific health needs.

Potential Side Effects

While Trifexis is considered safe, like any medication, it can have potential side effects. Some common side effects reported in dogs include vomiting, diarrhea, decreased appetite, lethargy, itching, and redness of the skin. These side effects are usually mild and temporary, but if they persist or worsen, it is important to contact your veterinarian.

Precautions for Border Collies

Border Collies may have a higher sensitivity to certain medications due to their genetic makeup. Some studies suggest that herding breeds, including Border Collies, may have a higher risk of adverse drug reactions. While there is no specific evidence linking Trifexis to adverse effects in Border Collies, it is always best to be cautious and consult with your veterinarian.

Some veterinarians may recommend monitoring your Border Collie closely after administering Trifexis for the first time to ensure they tolerate it well. If your dog has a history of allergies or sensitivities, it is essential to discuss this with your veterinarian before starting any new medication.

Alternatives to Trifexis

If you have concerns about using Trifexis for your Border Collie, there are alternative options available. Your veterinarian can suggest other flea and heartworm prevention medications that may be suitable for your dog based on their individual needs and sensitivities.


While Trifexis is generally considered safe for use in most dogs, including Border Collies, it is important to consult with your veterinarian and consider your dog’s specific health needs. Border Collies may have a higher sensitivity to certain medications, so it is crucial to monitor them closely for any adverse reactions. Always prioritize your pet’s well-being and work closely with your veterinarian to ensure the best care for your Border Collie.

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